• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Trifluoperazine dihydrochloride

CAS No. 440-17-5

Trifluoperazine dihydrochloride ( TFP | SKF5019 )

产品货号. M14498 CAS No. 440-17-5

一种抗肾上腺素能、抗多巴胺能和抗胆碱能化合物。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥405 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Trifluoperazine dihydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    一种抗肾上腺素能、抗多巴胺能和抗胆碱能化合物。
  • 产品描述
    An antiadrenergic, antidopaminergic and anticholinergic agent; is identified as an inhibitor that disrupts the S100A4/myosin-IIA interaction; block S100A4-mediated disassembly of myosin-IIA filaments, and promote S100A4 oligomerization.Schizophrenia Approved(In Vitro):Trifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
  • 体外实验
    Trifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
  • 体内实验
    ——
  • 同义词
    TFP | SKF5019
  • 通路
    GPCR/G Protein
  • 靶点
    Dopamine Receptor
  • 受体
    D2
  • 研究领域
    Neurological Disease
  • 适应症
    Schizophrenia

化学信息

  • CAS Number
    440-17-5
  • 分子量
    480.4174
  • 分子式
    C21H26Cl2F3N3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    FC(C(C=C1N2CCCN3CCN(C)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.[H]Cl.[H]Cl
  • 化学全称
    10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Malashkevich VN, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10. 2. Huerta-Bahena J, et al. Mol Pharmacol. 1983 Jan;23(1):67-70. 3. Creese I, et al. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):223-6.
产品手册
关联产品
  • DOV-216,303 Free Bas...

    DOV-216,303 Free Base 是一种血清素、去甲肾上腺素和多巴胺再摄取抑制剂,IC50 分别为 14、20 和 78 nM。

  • Fipexide

    Fipexide (Attentil, Vigilor) 是一种哌嗪类化学化合物。

  • Fananserin

    Fananserin 是一种有效的、选择性的、口服活性的 5-HT2 拮抗剂(对于大鼠 5-HT2A,Ki = 0.37 nM)。