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Trifluoperazine dihydrochloride
CAS No. 440-17-5
Trifluoperazine dihydrochloride ( TFP | SKF5019 )
产品货号. M14498 CAS No. 440-17-5
一种抗肾上腺素能、抗多巴胺能和抗胆碱能化合物。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
100MG | ¥405 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Trifluoperazine dihydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述一种抗肾上腺素能、抗多巴胺能和抗胆碱能化合物。
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产品描述An antiadrenergic, antidopaminergic and anticholinergic agent; is identified as an inhibitor that disrupts the S100A4/myosin-IIA interaction; block S100A4-mediated disassembly of myosin-IIA filaments, and promote S100A4 oligomerization.Schizophrenia Approved(In Vitro):Trifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
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体外实验Trifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
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体内实验——
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同义词TFP | SKF5019
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体D2
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研究领域Neurological Disease
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适应症Schizophrenia
化学信息
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CAS Number440-17-5
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分子量480.4174
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分子式C21H26Cl2F3N3S
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESFC(C(C=C1N2CCCN3CCN(C)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.[H]Cl.[H]Cl
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化学全称10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Malashkevich VN, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10.
2. Huerta-Bahena J, et al. Mol Pharmacol. 1983 Jan;23(1):67-70.
3. Creese I, et al. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):223-6.
产品手册
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